8 Cissus Quadrangularis Benefits, Side Effects, Pros & Cons, Dosage & Best Brand

Cissus quadrangularis is a perennial vine from the Vitaceae family. It’s also known as veldt grape, adamant creeper and winged treebine, and is mainly found in Asia and parts of Africa.

Traditionally, this plant has been used to heal wounds and bone fractures, and for inflammatory conditions like back and joint pain. Modern scientific studies also highlight its benefits for weight loss, arthritis, osteoporosis, bone health, stronger teeth, sporting injuries, and speeding up recovery from intense exercise.

Here’s how Cissus quadrangularis works, correct dosage and when to take it, potential side effects and precautions, overall pros and cons, and the best Cissus capsules to take if you’d like to try it for yourself.

8 Benefits of Cissus Quadrangularis and How to Take It

Ahead are 8 common reasons why people use Cissus supplements, including for testosterone, to lose weight, for stronger bones, better teeth, less painful joints, tendonitis, arthritis and osteoporosis.

There’s how it works and links to research studies if you’re interested. Or if you’re just looking for results then feel free to skip ahead to the recommended dosage and timing sections.

1. Cissus for Weight Loss

The main weight loss benefits of Cissus quadrangularis are inhibiting fat absorption and enhancing metabolic processes. It influences lipid metabolism, appetite regulation and fat storage. Taken regularly, this herb can be useful for helping you drop the pounds.

How Cissus Supplements Helps You Lose Weight

• Reduces Lipase Activity: Cissus quadrangularis contains compounds that suppress pancreatic lipase, the enzyme responsible for fat digestion. Reducing lipase activity can decrease the amount of dietary fats that are absorbed in your intestines. Used consistently, this action could lead to lower body fat storage from fatty meals.
• Increases Adiponectin Levels: This herb enhances a hormone called adiponectin that regulates glucose and the breakdown of fatty acids. Increasing circulating adiponectin can improve insulin sensitivity and promote fat oxidation, both of which are highly beneficial for weight loss.
• Regulates Serotonin: Studies showed an extract of Cissus quadrangularis can boost serotonin levels, which helps suppress appetite and reduce food cravings. Low serotonin is associated with hunger and binge eating, so it’s worth keeping this hormone in mind when you’re trying to lose weight.

Recommended Dosage and How to Take Cissus for Fat Loss

Experts usually recommend a daily dosage of 1,000 mg of Cissus extract for improving fat metabolism. Sometimes 1,500 mg is suggested for faster results. It should be taken with a meal for better absorption and less chance of side effects.

Having it with a light breakfast could be good for reducing mid-morning hunger pangs. On the other hand, if nighttime snacking is more of a problem for you (like it is with me), then it would be more helpful to take your Cissus capsules with dinner.

Even better, you could take 500 mg with breakfast and 1,000 mg with dinner, or vice versa, depending on when hunger between meals is the biggest problem for you.

Some herbal medicine practitioners recommend cycling Cissus quadrangularis. My research showed that 10 weeks is an often cited period to take this supplement before having a break of a couple of weeks.

The reasons given for cycling are to reduce the chances of tolerance and minimize potential side effects. Giving your body a break from herbal remedies like this can often make them more effective after you restart them again.

Double Wood Supplements has a high-quality Cissus quadrangularis extract with 150 capsules in the container. At the usual 2 capsules a day dose it will last you for just over 10 weeks.

I like this brand because they’re made in America in a GMP-certified facility and they show third-party testing certificates for safety, purity and potency on their product pages. This should be standard practice for nutritional companies in 2026. Unfortunately it’s rare.

They are also very good value with the welcome discount here on their website and further reductions for the multipacks, if you like to stock up and save like I do.

2. Cissus Quadrangularis and Testosterone

While it’s not a traditional bodybuilding or men’s health supplement, like Fadogia Agrestis, Maca, Turkesterone or Beta Ecdysterone, supplementing with Cissus quadrangularis may boost testosterone levels and support muscle growth. It primarily works by influencing hormonal balance.

Cissus for Muscle Building and Testosterone

• Ketosteroids: Cissus quadrangularis contains 3-ketosteroids, intermediates in the metabolism of androgens, estrogens and progestins. While in theory these compounds could be beneficial for hormonal health, more research is needed to prove whether 3-ketosteroids can stimulate anabolic activity and enhance testosterone production.
• Phytosterols: Beta-sitosterol, stigmasterol and other phytosterols found in the veldt grape plant are known to regulate estrogen levels. Reducing high levels of estrogen allows testosterone to work more effectively, promoting muscle growth, maintaining bone density, and improving male sex drive.
• Increased Insulin Sensitivity: This Research showed an extract of Cissus improved insulin sensitivity. This is important for muscle growth as this hormone is considered anabolic by most serious bodybuilders. Better insulin sensitivity allows for more efficient nutrient uptake in muscle cells, which leads to faster growth and better recovery from training.
• Reduced Cortisol Levels: Some studies found Cissus quadrangularis moderated cortisol by blocking its receptors. This stress hormone can interfere with testosterone production when it’s elevated to high. Lower cortisol levels also create a more favorable hormonal environment for both muscle gain and recovery from exercise.

How to Use Cissus Extract for Bodybuilding

From my research, men most often recommend this herb in bodybuilding forums for joint health and to assist with recovery from hard training, rather than for specifically boosting testosterone.

Keep in mind that high level bodybuilders often expect fast results. Cissus quadrangularis ketosterone supplements are unlikely to work as quickly as say Fadogia Agrestis or Beta Ecdysterone.

In my opinion, Cissus capsules would be more helpful for older men dealing with decreased insulin sensitivity, high cortisol and too much estrogen. In cases like this, it can help raise testosterone levels and build muscle, while also strengthening bones and protecting tendons and ligaments during training.

1,000 mg taken with the meal before your workout that day is a good starting dose for muscle building and testosterone with Cissus quadrangularis. This should maximize its anabolic effects during exercise, help to reduce muscle soreness and inflammation, and speed up recovery.

I take 2 of these capsules with independent potency and safety testing certificates shown on the product page. A single bottle will last you for 2 ½ months at the recommended 1,000 mg dosage, though the discounted multipacks are even better value.

3. Bone Healing, Fractures and Stronger Bones with Cissus

When taken regularly, Cissus quadrangularis has the unusual ability to improve bone density and speed up recovery from fractures. Supplementing with this herb can support bone strength and structural integrity over time. Here’s how it works.

How Cissus Root Improves Bone Health

• Osteogenic Properties: Cissus Quadrangularis extracts have been shown to stimulate the proliferation of osteoblasts, compounds central to bone healing and growth. It also aids in the synthesis of bone matrix proteins and regulates calcium metabolism, both important factors for maintaining bone density and strength.
• Reduces Inflammation: Research found Cissus extract has anti-inflammatory properties that can decrease pain and swelling around bone fracture sites. Reducing inflammation around broken bones allows them to heal faster and makes fractures easier to manage during recovery.
• High Calcium and Phosphorus Content: This plant is rich in both calcium and phosphorus, primary minerals for bone formation, maintenance and repair. Increased serum calcium levels can help to remineralize depleted hydroxyapatite within bone tissue, strengthening your bones and promoting faster healing when they are fractured.

Correct Dosage and How to Take Cissus Pills for Bone Healing

Cissus quadrangularis is a good preventative supplement for elderly women and men who are at a much higher risk of debilitating fractures from weakened bones. For general bone health, 1,000 mg is a commonly recommended daily dosage. It’s better absorbed when you take it with meals, so have it with breakfast and lunch or dinner.

For healing broken bones, a higher dose of 1,500 mg to 2,000 mg per day could be more effective. Studies showed that taking this herbal remedy reduced the usual fracture healing time from 14-16 weeks to 8-10 weeks, significantly speeding up recovery.

It’s important to take Cissus capsules regularly for best results. Getting the discounted multipacks here on the Double Wood Supplements site is a simple way to stock up and save. Their products are made in the USA in a GMP-certified facility, 3rd-party safety tested, and much cheaper per daily dose than brands like Himalaya, Cissus Supreme, or the overpriced CQR-300 formula.

4. Cissus Supplements for Teeth

Cissus root extract is also good for your teeth and general dental health due to its remineralizing, anti-inflammatory and antimicrobial properties. These beneficial effects may help prevent or even heal small cavities as well.

Supplementing with Cissus for Stronger Teeth and Preventing Cavities

• Remineralization of Teeth: This nutritious plant is rich in calcium and phosphorus, which are both needed for building up your tooth enamel. The same compounds in it that aid in healing broken bones also promote the remineralization of weakened teeth. Given the right conditions, this process could potentially reverse early-stage cavities as well.
• Anti-Inflammatory and Healing Properties: Cissus quadrangularis has anti-inflammatory effects that can improve gum health by reducing inflammation and promoting healing. This is also preventative for periodontal disease, which can lead to tooth decay and, in serious cases, require extraction.
• Antimicrobial Activity: Veldt grape extract contains flavonoids that can slow down bacterial growth in your mouth, particularly Streptococcus mutans. This harmful bacteria is a major contributor to tooth decay and reducing its prevalence lowers the risk of cavities and supports better oral health.

Taking Cissus for Dental Health

For stronger teeth and cavity prevention, a dosage of 1,000 mg daily is suggested. That’s usually 2 Cissus capsules. You can either take them together or have 1 with breakfast and another with lunch or dinner.

Like bones, teeth take a while to heal but improvements in dental health may be noticeable in around 1 to 2 months. Small cavities may also heal during this timeframe if conditions are right. For larger cavities, it’s best to visit a your dentist before they get worse.

5. Cissus Quadrangularis Benefits for Back Pain and Joint Problems

Cissus quadrangularis has anti-inflammatory properties that help with pain in places like your lower back, neck, hips, knees and other kinds of joint inflammation.

It also works to heal and build up damaged connective tissues. These actions can be particularly good for people suffering from conditions like osteoarthritis, rheumatoid arthritis, gout and other musculoskeletal issues.

How Cissus Works for Joint Pain

• Anti-Inflammatory Properties: The adamant creeper plant is rich in beta-sitosterol and flavonoids like luteolin that reduce inflammation in your joints and connective tissues. This can lessen pain and stiffness in places like your neck, back and knees, as well as improve mobility for people suffering from chronic joint conditions.
• Stimulates Connective Tissue Repair: This research noted that this herb stimulated fibroblasts and chondroblasts at the initial phase. These mesenchymal cells heal and repair your connective tissues. By enhancing the regeneration of cartilage and tendons, Cissus supplements can build up the strength and durability of your joints over time.
• Inhibits Pain Pathways: Cissus quadrangularis extract inhibits inflammatory mediators like cytokines that contribute to higher pain perception. This action can decrease the level of pain you feel in affected areas, particularly for people with chronic conditions like arthritis.
• Supports Bone Health: Taking Cissus pills regularly could enhance calcium and phosphorus uptake and improve bone density over time. This process is protective against conditions like osteoarthritis and osteoporosis. Stronger bones also provide better support for joints, and less discomfort when moving around.

How to Use Cissus Capsules for Painful Joints

For this natural remedy to be effective for lower back pain, stiff necks, aching knees and other painful joints it would be important to take it regularly. 1,000 mg is a commonly recommended dosage, though 1,500 mg a day, or a 500 mg capsule with each meal, should be even more effective.

Research like this demonstrated that noticeable improvements in joint function and musculoskeletal pain are often felt within 4 to 8 weeks of consistent use.

Boswellia is another very effective natural remedy for painful joints and chronic inflammation. There’s much more on the many benefits of Boswellia Serrata here, including weight loss, liver and gut health, better skin and how it helps with arthritis.

6. Cissus for Tendonitis and Sporting Injuries

Supplementing with Cissus extract can speed up healing with sporting injuries and particularly tendonitis. This is due to its anti-inflammatory properties and how it aids connective tissue repair. Compounds in this herbal remedy are beneficial for healing tendons and muscle strains, as well as recovering from hard workouts and heavy exercise.

Cissus Quadrangularis for Injury Recovery

• Repairs Connective Tissue Cells: This natural remedy stimulates the proliferation of fibroblasts, chondroblasts and osteoblasts. These mesenchymal cells are the building blocks of your connective tissues, cartilage and bones.
• Anti-Inflammatory Compounds: Cissus contains flavonoids and other compounds that reduce inflammation in tendons, ligaments and surrounding tissues. This action helps with pain from tendonitis or strained muscles and promotes faster recovery from injuries.

How to Use Cissus for Sporting Injuries and Tendonitis

For tendonitis, muscle strains and training recovery, a dosage of 1,000 mg to 1,500 mg of Cissus extract daily is often recommended. Research showed Cissus supplementation accelerated recovery from sporting injuries and reduced healing time compared to standard after-exercise protocols.

7. Arthritis and Cissus Quadrangularis

Cissus is a beneficial supplement for both osteoarthritis and rheumatoid arthritis sufferers. This is due to its anti-inflammatory properties and ability to support joint and bone health. It can reduce arthritic pain and swelling while working to regenerate connective tissues in joints and remineralize weakened bones.

How Cissus Works for Osteoarthritis and Rheumatoid Arthritis

• Anti-Inflammatory Compounds: Cissus quadrangularis contains flavonoids and phytosterols that counteract pro-inflammatory cytokines like IL-1β. These cytokines are directly involved in both the painful symptoms and further progression of osteoarthritis and rheumatoid arthritis.
• Supports Cartilage Repair and Bone Health: Cissus extract stimulates chondrocyte and osteoblast proliferation. These specialized cells build and maintain cartilage integrity and bone density respectively. By enhancing bone and cartilage regeneration, this herbal remedy works against the degenerative effects of both osteoarthritis and rheumatoid arthritis.
• Minerals and Antioxidants: Nutritionally, adamant creeper is rich in calcium, phosphorus and antioxidants like vitamin C, luteolin, beta-carotene and quercetin. Calcium and phosphorus are needed for healing and maintaining your bones, while antioxidants like quercetin and luteolin combat oxidative stress within your body, protecting your cells from damage.

Recommended Dosage and When to Take Cissus Supplements for Arthritis

1,000 mg of Cissus root extract daily would be a normal dose to assess your tolerance for this herb. If there are no side effects then a higher dose of 1,500 mg a day could be even more effective for managing arthritis symptoms. Larger amounts like this are better taken in spread-out doses with breakfast, lunch and/or dinner and well away from any prescriptions.

If you’d like to see how this natural remedy works for you then it’s important to take it consistently. Studies like this showed noticeable improvements in arthritic knee pain and better mobility for patients taking Cissus quadrangularis daily.

Double Wood’s Cissus extract is made in a GMP-certified American facility and third-party tested for potency, purity and safety. The best value is here on the brand’s website, particularly for the extra reduction with the multipacks. There are 150 capsules in each of those containers so they’d last you for 2 ½ months at the standard 2 capsule dose.

8. Cissus Extract for Osteoporosis

Cissus quadrangularis capsules are beneficial for osteoporosis because of the way this herb improves bone mineral density and speeds up the healing of fractures. Its anti-inflammatory and anabolic properties are particularly good for elderly men and women at risk of weakened bones.

Cissus Benefits for People with Osteoporosis or Osteopenia

• Strengthens Bones: The winged treebine plant contains compounds that promote osteoblast proliferation, which is central to bone formation and repairing fractures. Stimulating osteoblasts improves bone mineralization and helps counteract the negative effects of osteoporosis by increasing bone density.
• Inhibits Bone Resorption: Supplementing with this herb has been shown to counteract osteoclastogenesis, the process where osteoclasts break down bone tissue. By reducing the activity of these bone-resorbing cells, Cissus can preserve bone mass and prevent further deterioration for people with osteoporosis or osteopenia.

How to Take Cissus for Osteoporosis Prevention

Check with your doctor first, but if you’re dealing with osteoporosis, or at risk for it, then Cissus quadrangularis could be a good supplement to take regularly. The higher 1,500 mg daily dose is likely to be more effective and a capsule with each meal would be a smart way to take it.

People suffering from degenerative conditions like osteoporosis or arthritis can often benefit from a multipronged approach. Natural remedies for joint pain and inflammation like Turmeric, Boswellia, Glucosamine, Collagen, Ashwagandha and Cissus can work together and have synergistic effects when taken around the same time.

5 More Ways to Use This Natural Remedy

The veldt grape vine has been used in Ayurvedic medicine and other traditional healing practices for thousands of years. There’s a wide range of conditions and ailments it’s said to treat. Along with the 8 already covered above, here are 5 more beneficial effects of Cissus quadrangularis:

1. Digestive Health: In Ayurveda, this herb is known as Hadjod and often used to treat gastrointestinal issues like indigestion, constipation and flatulence. This is interesting since an upset stomach is sometimes considered a negative side effect of the powdered version.
2. Menstrual Disorders: The winged treebine plant is believed to aid in regulating hormonal cycles and be helpful for women experiencing irregular menstruation. Its analgesic properties are also good for alleviating pain and discomfort from menstrual cramps.
3. Respiratory Conditions: Hadjod is sometimes used to treat respiratory ailments and breathing difficulties, such as bronchitis and asthma. In Ayurvedic practice the plant was crushed up and made into a paste for topical application.
4. Wound Healing: Cissus stem, seed and root preparations have been applied topically to promote faster wound healing and to treat burns and insect bites. Herbal pastes were also applied to the site of fractures and this plant was even nicknamed ‘bone setter’.
5. General Tonic: In some cultures, Cissus quadrangularis is regarded as a general health tonic that can heal imbalances in the body and enhance overall well-being. It’s also thought to benefit both men’s and women’s reproductive health.

The Best Cissus Quadrangularis Supplement

There are a couple of important things I look for when buying herbal supplements like Cissus quadrangularis. The 1st is for it to be clearly stated that they are manufactured in a proper American cGMP facility, otherwise it might be made somewhere like China or India.

The 2nd thing I want to see is that it’s been independently tested to show that it contains exactly what’s on the supplement facts label. I also want proof that there are no contaminants, like bacteria or heavy metals, so I know it’s safe to take.

You would think this would be standard practice for nutritional products in 2026. Unfortunately, the FDA doesn’t require it and it’s exceedingly rare. The Double Wood brand is the only supplement company I’ve seen that shows certificates of analysis and safety testing right on their product pages.

Their Cissus root extract comes in a container with 150 capsules, much more than the usual 60 or 90 caps. Taking 2 pills a day gives you the most commonly recommended 1,000 mg dose and will last for around 2 ½ months when taken daily.

Some herbalists and nutritionists suggest taking a break of a week or 2 with this herb after 10 weeks of consistent use. I think cycling is a good idea and it’s easier to remember if it’s timed with when you finish the bottle.

For all its benefits, Cissus can be pretty inexpensive to take. Double Wood has a welcome discount here and further reductions for the multipacks. If you take advantage of those it brings the monthly costs down significantly. There’s also complimentary shipping on all orders within the United States.

Potential Side Effects and Precautions

Side Effects of Cissus Quadrangularis

This herbal remedy is generally well-tolerated when taken at regular doses and with food. Like most natural treatments, a small number of people have negative effects, particularly when used on an empty stomach or in higher amounts. The most common Cissus side effects reported include:

1. Gastrointestinal Issues: In customer reviews, people occasionally talk about symptoms like gas, an upset stomach, intestinal pain or diarrhea. These digestive problems aren’t common but worth being aware of.
2. Headaches or Sleeplessness: Some users have reported getting a headache or having trouble sleeping after using Cissus quadrangularis. Taking a day or 2 off and then lowering the dosage by half usually stops side effects like these. If any supplement is disruptive to a person’s sleep then it’s best to avoid taking it in the evening.
3. Diuretic Effects and a Dry Mouth: Herbalists say this plant can have a mild diuretic effect for some people, meaning it helps your body get rid of excess fluids. That can be good for dealing with fluid retention and even lead to some temporary weight loss. A dry mouth may be a side effect though if you’re not drinking enough water.
4. Allergic Reactions: Although very rare, allergic reactions can sometimes occur, especially for people who are sensitive to grapes and other plants in the Vitaceae family.

Precautions with Cissus Pills

1. Avoid When Pregnant: Doctors usually advise pregnant or breastfeeding women to avoid using this herb since no long-term studies have been done on its safety during pregnancy.
2. Not With Prescriptions: People with too much sugar in their bloodstream and taking prescriptions should consult their physician before using Cissus. As a general rule, all potent natural remedies like this should be taken well away from anything your physician gives you to take.
3. Increases Calcium: The veldt grape vine is high in calcium nutritionally and enhances its uptake so people with kidney stones or similar issues should be cautious. Always check with your healthcare provider before taking supplements if you are being treated for any conditions.

Customer Reviews and Consumer Reports

Here’s some examples of what I found going through consumer feedback and buyer ratings for Double Wood’s Cissus root extract. I always look for common themes and effects that a number of people are talking about in reviews, rather than one off reports as I don’t find them trustworthy.

Themes in Positive Ratings

1. Helps with Pain from Arthritis and Osteoporosis: Many people said they had less pain once they started taking these Cissus capsules. Some customer quotes:

• “I am in tears writing this review. I have Sacroiliac disease and a very painful lower back and hip pain. In other words, I have arthritis in these areas. Have spent countless thousands treating this disease… I take this and within 30 minutes my pain is gone. I’ve never had results like this before.”
• “I bought this because I have osteoporosis and also a little arthritis. I have pain from both. It has helped quite a bit. I have not been diligent about taking it and it still has helped.”

2. Weight Loss, Muscle Soreness and Joint Pain Relief: Customers mentioned this supplement being good for losing weight, post-workout soreness and less body aches. Some quotes:

• “I’m now on my third bottle, and I will tell you that this stuff really works. I mostly bought it for weight management, but have also noticed that my joints aren’t bothering me anymore.”
• “I was recommended this particular Cissus product by my bodybuilder friend… My physical therapist noted a positive difference in my hands after week 1 and I am noticing positive weight loss results. I also do not feel post-workout soreness that I usually feel after a heavy workout.”

3. Heals Connective Tissues: Consumers report this Cissus is helpful for problems with ligaments and tendons. Some examples:

• “The reason I bought this was because the ligament on my heel became so painful, it would take about 5 minutes to put all my weight on my foot. The pain was excruciating. 4 days of taking this and the pain is almost gone. I can’t believe the flexibility change.”
• “I was suffering from patellar tendinitis in my left knee and have been unable to run for 8 weeks. I read about Cissus in a years old thread on some bodybuilding forum and the ‘bros’ were raving about it so I thought why not. I’m probably at 90% now a week in and improving every day. Pain in day to day activity is completely gone.”

Negative Feedback

There were comparatively few reported side effects from this supplement versus the positive consumer reviews. As with most nutritional products, 1 and 2-star feedback is usually from people who didn’t feel like they got the results they were looking for. Some customer quotes:

• “I’m not really sure what benefit this has been giving me, I bought it on a recommendation that it would help shoulder pain as it’s apparently an anti-inflammatory supplement.”
• “I purchased this product for weight loss. I took it for several months and didn’t see any results.”

Pros and Cons of Cissus Quadrangularis

Pros of Taking Cissus Supplements

1. Improves Bone Health: Cissus quadrangularis can enhance bone mineral density and speed up the healing of fractures by stimulating osteoblast activity. This natural remedy is particularly good for older men and women at risk of brittle bones and osteoporosis.
2. Anti-Inflammatory Effects: This plant contains flavonoids and phytosterols that reduce inflammation and joint pain in conditions like osteoarthritis and rheumatoid arthritis. Its anti-inflammatory actions can aid in reducing arthritic pain and improving mobility.
3. Benefits for Weight Loss: Some studies like this suggest that Cissus quadrangularis supplements may help you lose weight if taken regularly. It increases adiponectin and reduces lipase activity, potentially helping to lower body fat storage after fatty meals.
4. Joint and Connective Tissue Support: Veldt grape contains compounds that enhance the regeneration of cartilage and tendons. As well as anti-inflammatory properties that can ease symptoms for people suffering from joint pain and arthritis.
5. Muscle Relaxation: This supplement has muscle-relaxing and healing properties that are especially beneficial for bodybuilders and athletes post-exercise. Taking it may aid in recovery after intense workouts and reduce muscle soreness and stiffness.
6. Antioxidant Properties: Cissus quadrangularis is rich in antioxidants like luteolin, vitamin C, beta-carotene and quercetin. These compounds combat oxidative stress within your body and contribute to overall health by protecting your cells from damage.
7. Strengthens Teeth: The winged treebine plant is high in calcium and phosphorus nutritionally and its anti-inflammatory and remineralizing properties are good for stronger tooth enamel, less chance of cavities and better dental health in general.
8. May Help with Testosterone: This herb contains ketosteroids, beta-sitosterol and stigmasterol for hormone regulation. Research shows it may improve insulin sensitivity and moderate cortisol. Both of these actions are positive for muscle building and testosterone.
9. Faster Recovery from Injuries: Taking Cissus extract can speed up the healing process for various sports injuries, like tendonitis, muscle strains, cartilage damage and even bone fractures. Its compounds stimulate connective tissue regeneration and supplementing with it may aid in training recovery for athletes and bodybuilders. 

Cons of Cissus Quadrangularis

1. Gastrointestinal Issues: Some people say they get gas, abdominal pain or even diarrhea when they take this supplement. Problems like these are usually avoided by sticking to the regular dose and always taking it with meals where it’s better absorbed anyway.
2. Neurological Effects: Headaches and sleeplessness have been reported by some people while using this natural remedy. It’s best to lower the dose and avoid taking it in the evening if you ever have side effects like this.
3. Diuretic and a Dry Mouth: Cissus tablets can have a mild diuretic effect. This can help with fluid retention but some people have reported a dry mouth when they take it. It’s sensible to drink it with a big glass of water every time and stay well hydrated.
4. Not for Everyone: This herb isn’t recommended for breast-feeding or pregnant women, those taking certain prescriptions, people with kidney stones and people allergic to grapes and similar plants.

What is Cissus Good For?

Cissus Quadrangularis is beneficial for fat metabolism and losing weight; building stronger bones and teeth; muscle strains, training recovery and sporting injuries; painful joints, arthritis, osteoporosis and musculoskeletal health in general.

This herbal extract also combines well with other natural remedies for joint pain and inflammation, like Boswellia, Turmeric, Ashwagandha, Glucosamine and Collagen here.

Thank you for making it all the way through my article on the many health benefits of Cissus Quadrangularis and how to use it. I hope it’s been interesting to read and helpful. If you have any more questions about this healing plant and how it works then please share them in the comments below.