Organifi Pure Review: Ingredients, Pros and Cons, Side Effects and Does It Work?

Pure Smart PacksCan a powdered superfood supplement improve your ability to concentrate, reduce stress, protect your brain cells and promote effective digestive function?

It’s a lot to ask but scientific studies are showing it is possible by supporting the gut-brain axis — the recently discovered link between cognitive function and your intestinal microbiome.

This review of Organifi Pure covers its ingredients, pros and cons, where to get it, directions, side effects and how this new gut and brain health formula works.

What Is Organifi Pure?

Many of us live busy and stressful lives these days and regularly experience anxiety, brain fog, mental fatigue and other symptoms of cognitive strain.

At the same time, gastrointestinal problems have become one of the most common reasons to visit a GP in America.

The two are in fact closely related. Stress negatively impacts digestion and an unbalanced GI tract heavily limits important neurotransmitter production.

Organifi Pure is a blend of superfoods and enzymes designed to improve cognitive function and mental focus, reduce stress and anxiety, and heal gastrointestinal issues by focusing on the brain-gut axis.

Formulated to support the Vagus nerve connection between your brain and your gut, and feed friendly bacteria for a well-functioning intestinal microbiome, Pure by Organifi is an ambitious nootropic and digestive health supplement.

Let’s look at what’s in it.

Supplement Facts

Here is the Organifi Pure ingredients label from the company’s website:

Organifi Pure Supplement Facts Label

Calories, carbohydrates, protein, and even the more common vitamins and minerals are not that relevant with these types of powdered supplements. This is not what they are designed to deliver.

What is important, in deciding whether this product works, is the specific ingredients in the Brain Support and Gut Support proprietary blends and the nutrients they provide.

Ingredients and Beneficial Effects

1. Lion’s Mane

Hericium Erinaceus, commonly known as Lion’s Mane mushroom or Yamabushitake, is highly prized in Traditional Chinese Medicine to assist the five internal organs (heart, liver, spleen, lungs & kidneys). It is also used to aid digestion.

Modern science shows it is rich in bioactive compounds, such as beta-glucans, hericenones, isoindolinones, erinacine terpenoids and other myconutrients, which have neuroprotective and neuroregenerative properties.

Lion's mane mushroom for NGF

Studies reveal Lion’s Mane has a unique ability to increase Nerve Growth Factor (NGF), a protective neuropeptide and neurotrophic factor involved in the growth and maintenance of neurons within your nervous system.

Peer-reviewed research has also shown compounds in Lion’s Mane promote neuron differentiation, thus helping your brain form new neural connections.

By increasing NGF, Lion’s Mane can have wide-ranging cognitive benefits, including improving mood, reducing stress and anxiety, and enhancing mental focus and concentration.

2. Baobab Fruit

African Baobab Fruit is particularly high in antioxidant polyphenols for combating free radical damage. These antioxidants help protect the integrity of your brain cells and guard against cognitive decline.

Baobab is also known for improving digestion, reducing inflammation, regulating sugar spikes and increasing iron absorption with its significant levels of vitamin C.

3. Aloe Vera

A potent digestive healer, the polysaccharides in Aloe Vera have anti-inflammatory qualities to soothe the mucosal tissues in the gut.

Aloe also helps improve your body’s immune response with its broad range of nutrients and immunostimulants.

This hydrating herb is even good for your skin’s complexion, with cooling, antibacterial and antiseptic properties.Organify Pure Lemon Flavored

4. Ginger Root

Well known around the world as a digestion aid, ginger has a beneficial effect on your entire gastrointestinal tract.

It also improves your body’s defenses, is a natural detoxifier, eases muscle cramps and elevates mental functioning.

Ginger consumption enhances the thermic effect of food as well, making it a helpful weight loss aid when taken regularly.

5. Monk Fruit

This sub-tropical melon, also known as Luo Han Guo, is 300-400 times sweeter than sugar. Yet it has no calories and does not cause sugar spikes.

This makes Monk Fruit a premier natural sweetener. If only more companies like Organifi would use it, instead of corn syrup, sugar or artificial sweeteners, we’d all be a lot slimmer and healthier.

6. Digestive Enzymes

Rarely seen in brain-focused blends like this, Organifi Pure ingredients include amylase, protease, lipase, cellulase and lactase. These enzymes improve food breakdown and assimilation and help bring your gut flora back into balance.

Lactase, for digesting milk sugar, is particularly useful as most people lack enough of it to deal with the dairy in their diet and suffer the side effects of bloating and gas.

7. Coffeeberry

Recent research has found that the bright red coffee fruit that surrounds coffee beans is a nutrient-rich superfood in its own right.

Coffeeberry has been demonstrated to increase Brain-Derived Neurotrophic Factor (BDNF), a neurotrophin protein which protects nerve cells and increases mental clarity and focus.Coffee Berry for BDNF

BDNF improves neural communication and is also involved in building new pathways within your brain, enhancing memory and helping you to learn faster.

The Vagus nerve connects your brain to your gut and modulates BDNF expression. The two are heavily reliant on each other for optimal functioning and the Pure formula aims to support both with its ingredients.

8. Lemon

A cleansing citrus fruit and rich in vitamins and minerals, Lemon aids immunity and has antibacterial, antiseptic and anti-inflammatory properties.

Lemons are also known for their high levels of antioxidants, appetite suppression, kidney cleansing and beneficial effects on skin tone.

9. Apple Cider Vinegar

ACV has an alkalizing effect to combat acidity and bring your body’s pH levels back into balance.

Apple Cider Vinegar also increases satiety and aids healthy digestion.

10. Coconut Water

A favorite of athletes, coconut water is full of electrolytes like potassium to enhance energy levels, performance and endurance.

It also increases nutrient absorption and has a potent hydrating effect throughout your body.

11. Tapioca Fiber Prebiotic

Once again focusing on the importance of the gut-brain axis, Tapioca fiber is a prebiotic that feeds beneficial intestinal bacteria and supports a healthy microbiome.

Science is now discovering that your gut flora are largely responsible for producing neurochemicals that your brain uses to regulate mental processes such as learning, mood, memory and relaxation.Pure Go Packs by Organify

Pros and Cons of Organifi Pure


1. All Ingredients are Organic and High Quality

Every addition to the Pure formula is certified USDA organic and serves a specific purpose in the supplement’s aim of improving mood, memory and mental focus by supporting the brain-gut axis.

The smaller number of ingredients means they are delivered in effective amounts, not in such small doses as to be insignificant. There are also no cheap fillers, as is the case with many other powdered supplement brands.

2. Brain-Protective Lion’s Mane, Coffee Fruit and Baobab

Neurofactor Coffeeberry extract is proven in human studies to increase levels of Brain-Derived Neurotrophic Factor. BDNF is associated with memory, learning, adaptation and general cognitive well-being.

Lion’s Mane mushroom increases Nerve Growth Factor (NGF), which has specific effects for reducing anxiety, improving mood and increasing mental energy and focus.

Polyphenol-rich Baobab protects your brain cells against free radical damage which can lead to cognitive decline. Aloe, Lemon and Ginger are other high antioxidant additions to Pure powder.Easy to Mix Pure Go Packs

3. Superfoods and Enzymes for Digestive Wellbeing

Aloe Vera is full of anti-inflammatory polysaccharides that soothe the gut and heal the mucosal tissue of intestinal linings.

Ginger, Lemon, Apple Cider Vinegar, Coconut Water, Baobab and Lion’s Mane are also beneficial for proper digestion.

Enzymes in Organifi Pure help break down carbohydrates, proteins, fats, fiber and milk sugar. While prebiotic Tapioca feeds friendly gut flora for a happier microbiome.

4. Convenient Single Serving Smart Packs

Due to the potency of this product it’s necessary to get the dosage right. That’s why Pure comes in precise 9.13 gram single serving size satchels.

You can easily pour and stir the powder into a glass of water ready to drink, whether you’re at home, at work, or on the go anywhere.

As well as being convenient, these Pure Go Packs also protect the formula from oxidation, increasing shelf life and maintaining nutrient potency.

5. Mild Taste with No Added Sugar

Customer reviews are predominantly positive on the taste of Organifi Pure Juice, despite the fact that it has no added sugar. Using zero-calorie Monk Fruit as a sweetener makes it helpful as a weight loss aid as well.

It is also certified USDA organic, non-GMO, vegan, keto-friendly and free of gluten, soy and dairy.


1. Not Cheap at Retail

Ingredients like Neurofactor Coffeeberry extract, Lion’s Mane, Baobab, Monk Fruit and digestive enzymes are expensive in their own right.

It’s not surprising then that Pure by Organifi isn’t a cheap supplement if you get it at the retail price at Amazon, Walmart, eBay or other online stores.

You can, however, get it for much less. This Organifi Gold review has how and it works for the entire Organifi range.

Organify Pure Juice

Side Effects

Pure powder is safe to use and there are no listed precautions or specific warnings on the company’s website.

Discuss taking it with your GP though if you are pregnant or on prescriptions.

Potential side effects of Organifi Pure could include:

  1. An over energizing effect due to a sensitivity to ingredients like Coffeeberry extract and Lion’s Mane. It’s recommended not to take Pure Go Packs in the evening unless you want to stay up working as it may affect your ability to get to sleep.
  2. A mild initial increase in bloating and gas due to prebiotic Tapioca starch. Prebiotics usually reduce digestive problems over time but can initially provoke some extra belly boat and flatulence.
  3. Lion’s Mane is considered very safe, even at large doses, though an allergic reaction has been observed in people with a mushroom allergy. Aloe Vera can also cause side effects like diarrhea and cramps at high intakes so keep to the recommended dosage.

Directions for Use

Taking Pure by Organifi couldn’t be easier. Simply open a single serving Smart Pack, pour the powder into a glass of water, stir and drink immediately.

You could also mix it into juice, though the taste in water is a mild, slightly sweet and creamy lemon flavor that most people should enjoy.

When to Take It

For best results have this gut and brain nutritional supplement first thing in the morning on an empty stomach before breakfast.

You could also use Organifi Go Packs as a mid-afternoon pick me up. Once again, positive effects are more pronounced when taken well away from food.Pure Go Packs by Organify

Does Organifi Pure Work?

The ingredients in this superfood powder, like a Lion’s Mane and Coffeeberry extract, have been proven in scientific studies to have specific actions on Nerve Growth Factor and Brain-Derived Neurotrophic Factor respectively.

Most of the other foods and herbs in the formula are well-known and often recommended in natural therapies for better digestive wellness.

While the amylase, protease, lipase and lactase enzymes improve digestion and reduce intestinal issues like bloating and gas from lactose in dairy.

Whether Organifi Pure will work for you personally depends on the current state of your gut microbiome and whether your body is lacking in the specific nutrients this organic supplement provides.

Some people may see no immediate results from taking powdered formulas like this and then claim that they are a scam or fraud. Though this makes little sense if others are getting noticeable benefits from taking it.

Ultimately, the only way to find out is to take the product yourself, consistently for at least a month, and take notice of how it affects you personally.

If it works to improve your mental clarity, memory and mood, as well as relieving digestive issues, the beneficial effects may make it well worth it for you. Pure nootropic supplement by Organify

Verdict And Product Rating

Organifi Pure is a potent superfood formula with high quality and organic ingredients. It is specifically aimed at improving cognitive function, reducing stress and supporting healthy digestive function.

It is unusual to see a formulation specifically designed to support the gut-brain axis, though there are scientific studies on Lion’s Mane and Coffeeberry extract in particular for this purpose.

It’s not cheap, but neither are the ingredients to get separately. It also won’t work for everyone, as those with a balanced gut microbiome and already high levels of BDNF and Nerve Growth Factor may not notice much difference.

However, if you are lacking in these areas, with symptoms like brain fog, forgetfulness, high stress and poor digestion, or just need to ensure that your cognitive performance is at its best, then Organifi Pure could make a real difference in your day.

With over 10 years experience in researching and writing about superfoods, it’s my opinion that a lot of thought has been put into this formulation and there are many potential benefits from taking it.

4.5 stars rating for Organifi Pure for the right customer: someone in need of its specific actions and who can afford to take it consistently for a month to see how it works.

For nutritional support focused more on healing and cleansing your body, consider Organifi Green Juice reviewed here.

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