How to Use Papaya Leaf Juice for Dengue Fever

Papaya leaf dengue cureCould papaya leaf juice be a natural treatment for dengue fever? This page examines the research, how to prepare papaya leaves for dengue and my personal experience with using papaya leaf juice for dengue fever.

What is Dengue?

Dengue fever, also known as breakbone fever, is a debilitating viral disease, prevalent primarily in the tropics and reported in over 120 countries. It is transmitted by the Aedes mosquito, a small mosquito with white dots or stripes over its abdomen, which is most active at dusk and dawn.

Symptoms appear within 5 to 7 days of being bitten by an infected mosquito and include high fever, extreme lethargy, headaches, severe joint and muscle pain, skin rash, nausea and pain behind the eyes. In a small percentage of cases, the viral infection can develop into dengue hemorrhagic fever, a severe and potentially life-threatening condition.

According to the WHO, dengue infections have increased dramatically in recent years and, on current estimates, approximately 390 million people are infected a year worldwide. Ten times this number live in an area where they are at heightened risk of contracting dengue fever. Clearly this is a serious and growing health problem.

Although there are currently no pharmaceuticals available to treat dengue, it is still very important to be monitored by a doctor when suffering from the disease. By testing your blood, they can check that your white blood cell and platelet count are not dropping too low and that you are not at risk of dengue hemorrhagic fever.

Papaya Leaf Juice for Dengue

While there is no drug-based treatment for the disease, a popular natural remedy for dengue is papaya leaf juice. Many people report significant improvement in dengue symptoms from drinking the juice of papaya leaves and several studies have been done by doctors as to the effectiveness of this natural treatment.

This study, done by a Sri Lankan doctor, followed 12 patients diagnosed with dengue and low platelet count. They were given a 5 mL dose papaya leaf extract, obtained by crushing fresh papaya leaves, at eight hour intervals.

Afterwards, all 12 patients with dengue were found to have elevated white blood cell counts and platelet counts, many significantly, in the day after the treatment was first administered. Dengue fever is known to drop platelet count and white blood cell levels, often dramatically, yet the papaya leaf cure seemed to reverse the usual progression of the disease.

None of the 12 patients required hospitalization following the papaya leaf juice administration and 5 patients with itching hemorrhagic skin rash found that it disappeared within 2 days of the treatment.

This Malaysian Ministry of Health website article discusses a randomized controlled trial on 228 hospital patients with dengue fever. In the trial, half were given papaya leaf juice for 3 days and experienced a significant increase in platelet count versus the control group.

Another study on Pubmed showed dramatic improvement using papaya leaf extract in a severe case of dengue fever and this review of the current literature concerning papaya leaf and dengue concluded that “…it appears that C. papaya leaf extract does have beneficial properties in dengue. It has been shown to bring about a rapid increase in platelet count.”

Important Warning for Pregnant Women

Unfortunately, papaya leaf juice cannot be recommended for women who are pregnant and contract dengue. Papain, the potent proteolytic enzyme found abundantly in papaya leaf, papaya seeds and green papaya, is known to induce miscarriages and could be dangerous to your unborn baby.

Please do not juice papaya leaf or papaya seeds for dengue fever during pregnancy. There’s more on the potential side effects of papain from papaya here.

Personal Experience with Dengue

Recently, my girlfriend and I traveled to Koh Tao in Thailand. Near the end of the holiday she developed a fever, skin rash, muscle and joint pain and was so weak she found it hard to walk. The symptoms came on very quickly as she had been fine the day before.

Papaya leaves dengueWe went to a clinic on the island as there was no hospital. They took a blood test and were so concerned they kept her in the clinic overnight on a drip while they waited for the results to come in.

The next morning it was confirmed that she had dengue fever and she was transported, under medical supervision, to the larger island of Koh Samui the same day to be treated at a hospital.

While her symptoms were bad at the start, she did seem to recover very quickly. Her initial blood test showed her white blood cells were at 1.63 L, which is quite low when the normal average is between 4.3 and 10.8. Her platelet count was at 175,000, with 150,000 to 450,000 considered normal.

Subsequent blood tests over the following days (which I unfortunately don’t have access to now but did see at the time), showed both white blood cells and platelet count increased, rather than dipped as the doctor had told us to expect.

On day 4, after seeing her latest blood test, the doctor wrote on her sheet “dengue without complications”. By day 6 both white blood cells and platelets were significantly increased and she was told she had beaten the infection and was fit to fly.

This is a very good result as dengue fever is usually at least a 7-day infection with many reporting several weeks of symptoms. Even with a long flight back only 6 days after first being diagnosed, she seemed to have recovered well from dengue.

What We Did to Treat Dengue with Papaya Leaf Juice and Papaya Seeds

While I have no definite proof that what I’m about to share helped by girlfriend recover from the disease, the doctor did seem surprised that her blood tests were so positive. She’d previously warned us that the dengue infection would be a lot worse.

From my research on the beneficial properties of papaya seeds and papaya leaf as a cancer treatment, I knew the plant had some powerful enzymes like papain and chymopapain and alkaloids such as carpaine, as well as a wealth of flavonoids and other beneficial compounds.

From the first night she had to stay in the clinic, I found a fresh papaya for her and she ate around a tablespoon of papaya seeds, chewed up and eaten with the fruit. This was repeated again in the morning, which was day 2 of the infection.

Both papaya seeds and papaya leaves are known to contain similar substances, though I suspect the seeds are best for parasites (and possibly malaria), while the juice of papaya leaves is most often given for dengue.

On day 3, I found a fruiting papaya tree in the local area and took a medium sized and relatively young leaf from the lower part of it. It was a little lighter green than the fully matured dark green leaves up the top of the plant.

After washing it and pulling off the woody stem, I took it to a restaurant that made fruit smoothies and got them to blend it up with coconut water and pineapple.

I had a good dose of this myself first and had no side effects, though I have to be honest, it didn’t taste at all great. She had this blended papaya leaf, which would equate to a good dose of the juice, on the afternoon of day 3 and the morning of day 4. From my observation, her condition improved significantly after this.

On day 5, I found a juicing shop and took another two young papaya leaves to them and had them added to a freshly made juice with pineapple, celery and beet, a known blood builder and liver toxic.

She drank this juice, admittedly reluctantly as it tasted pretty terrible, on the afternoon of day 5 and on day 6, after her third blood test, was declared by the doctor to have beaten dengue.

In a difficult situation, without my usual equipment, I wasn’t able to prepare exact dosages like the studies above, or even a consistent method of delivering the papaya enzymes, alkaloids and other compounds. Regardless, it’s my personal belief that papaya leaf and perhaps the seeds made a big difference to her quick recovery from dengue fever over those 6 days.

Recommended Methods for Preparing Papaya Leaf for Dengue

The most commonly recommended method for using papaya leaves for dengue is to first obtain fresh papaya leaves from a growing papaya tree. In many tropical destinations papaya trees are easily found locally. You want the younger leaves at the lower part of the tree that haven’t yet reached their full size.

Ideally, they should be from a fruiting tree, as this confirms that is a true papaya plant. If you can’t find a tree that is fruiting then study online images of papaya leaves closely to make sure you get the right plant. Similar sized and shaped trees may be toxic, though the papaya leaves themselves are distinctive. Check with a local if possible.

Take them to a sink and wash them well then tear off the fibrous stem. You only want the young green leaves. Some resources recommend deveining these of their center part as well, though I didn’t do this.

Next they need to be either juiced if you have a juicer, or crushed up and the juice squeezed out. You can use a filter cloth and pound the leaves to extract the juice. Alternatively, crush them up in a large mortar and pestle, or on a chopping board with the bottom of a jar and then squeeze out all the juice you can with your fingers.

Usually only about 1 tablespoon of papaya leaf juice is obtained from a crushed leaf so crushing up 2 is recommended if you have to use this method.

Take the juice at least twice a day, or every 6 hours if possible, on an empty stomach and diluting it with a bit of water. It’s best to hold your nose and shot the papaya leaf juice down as the taste isn’t pleasant.

Realistically, for people traveling who contract dengue, or those who don’t have the equipment to prepare the papaya leaves, finding a juicing shop and taking the leaves to them as I did is the simplest method. When I went to the juicing place in Koh Samui near the hospital they told me other people had come to them in the past with the same request.

Choose a healthy juice option and get them to juice your washed papaya leaves with it. I chose one with beets for the liver benefits and pineapple for its bromelain. If they had papaya juice available I would’ve used that as well.

You can try adding lots of sweet fruits but realistically the juice is not going to taste good. It will be bitter and hard to drink but I think most people would deal with that to speed up their recovery from dengue with papaya leaf. Don’t add sugar as you need your body healthy and sugar only damages it.

Papaya leaf is also often recommended for treating malaria and for this purpose it is regularly boiled and taken as a tea. While this method may work for preventing or recovering from malaria, it isn’t recommended for dengue fever. Use the fresh, unheated papaya leaf juice only.

The Natural Treatment for Dengue Fever

If you’re suffering from dengue then it’s important to visit a doctor and have your blood tested for white blood cell and platelet count every couple of days. Beyond that, and making sure you stay well hydrated, there’s not a lot modern medicine can do for this debilitating illness.

Fresh papaya leaf juice is a natural treatment for dengue fever that is gaining popularity because, in both small studies and many people’s personal experiences, the effect on recovering from dengue is dramatic.

I’d appreciate hearing from anyone who has tried using papaya leaf juice for dengue or malaria in the comments below, especially how you prepared it and any blood test results you had.

Please share this page with your friends as well. Even if you don’t live in an area where dengue fever is common, many people travel to tropical destinations where it is and need to know that there is a dengue natural treatment available for this terrible disease.

Photo 1 and 2: Public Domain /Photo 3: Richard Parker

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Back when I was a US Peace Corps volunteer in the Philippines, I contracted dengue fever and spent spent a week in the hospital. I now live in the same island with papaya trees growing in the yard. I’m now enjoying the taste and many benefits of eating papaya fruit.
Surprisingly here where dengue can be a problem, I haven’t heard any feedback locally in the news about this as a treatment. I’m now surely going to eat papaya seeds for digestive health, but if need be I would surely try papaya leaves for dengue.
Thanks so much for the valuable information!

    Jim Dillan

    Thanks for your comments Queenie.

    The papaya leaf cure for dengue doesn’t seem to be widely known but some of the locals I spoke to in Thailand had heard of it. I’d appreciate if you could share it on social media to spread the word.

    Admittedly papaya leaf juice does taste pretty bad but it’s well worth it to help you recover from dengue fever.

    All the best,



Yes in india it is well known by all the locals where i live. There is not a single dengue patient who has not taken it. Mainly for maintaining platelet count.

Azman [email protected]

It is known in Malaysia that papaya leaf juice is been used to cure dengue fever. Besides papaya leaf, there were using crab soup remedy for the same dengue fever.

Saroosh sulaiman

Platelet count was 1.02 lakh and we started to give her papaya leaves past 2 times a day for five days and now her count reach to 3.35 lakh
Patient age is 62
At Kolkata


I live in Delhi, Every Year dengue patients are given papaya leave juice & that has a miraculous effect on the platelet count of every patient. they recover very fast in a day or 2 , even those patients whose platelet count is very low it increases it very fast , people see the result in a first dose only.

    Jim Dillan

    Hi Rajat and thanks for your comments. Few people in Western countries seem to know about how well papaya leaf juice works for dengue fever, even though the disease is spreading and there is no drug based treatment.

    All the best,



Thanks for this timely information. The ades mosquito is said to be also responsible for the zika virus. Do u know if papaya leaves and seeds might also be used in treating males who become infected with the virus. I am saying male because of the side effects in the childbearing female
Your comments please

    Jim Dillan

    Hi Cassandra and thanks for your comments. I’ve actually written about using papaya leaf juice for zika here

    I believe it should certainly help recovery for males (you’re right on pregnant females as I highlight in that article). The question is whether the virus would still linger even after recovery and be an issue. There’s no clear research on this to my knowledge.

    All the best,



Hi , I live in Philippines and I had dengue in December of 2015. I heard about papaya leaves extract as a cure to dengue so I tried that. The best thing to do is to add honey to the extract to lessen the bitter taste of it. I had fever for several days and had to be confined at the hospital when my platelet count was below 100 (normal is 150-400). Had lots of 100% fruit juices, took vit.c tablets and had plenty of water to help hydrate myself since they said the virus will easily dehydrate the patients. Luckily, I only stayed one night at the hospital :), and thanks to papaya extract.

    Jim Dillan

    Hi Madilyn and thanks for your comments. Dengue is horrible and I believe it’s important to spread the word on using papaya leaves as a treatment for it.

    All the best,



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